Prostate Cancer - A brief review
Posted by Dr G [GNN] on Tuesday, May 19, 2015 Under: Health & Medical
This review of Prostate cancer is by Dr Sheldon Marks, MD, a specialist in Prostate cancer.
SOURCES: Prostate Cancer Foundation.
Prostate Cancer Research Institute. National Library of Medicine.
National Prostate Cancer Coalition. National Cancer Institute.
Understanding Prostate Cancer -- the Basics
What Is the Prostate?
The prostate is a gland in the male reproductive system. It makes
most of the semen that carries sperm. The walnut-sized gland is located
beneath the bladder and surrounds the upper part of the urethra, the
tube that carries urine from the bladder.
Prostate cancer is a major health concern for American men. The
disease is rare before age 50, and experts believe that most elderly men
have traces of it.
In 2013, about 238,500 new cases will be diagnosed in the U.S.,
and about 29,700 will die of it. African-American men are more likely to
get prostate cancer and have the highest death rate. In other parts of
the world -- notably Asia, Africa, and Latin America -- prostate cancer
is rare.
Prostate cancer is usually a very slow growing cancer, often
causing no symptoms until it is in an advanced stage. Most men with
prostate cancer die of other causes, and many never know that they have
the disease. But once prostate cancer begins to grow quickly or spreads
outside the prostate, it is dangerous.
Prostate cancer in its early stages (when it’s only found in the
prostate gland) can be treated with very good chances for survival.
Fortunately, about 85% of American men with prostate cancer are
diagnosed in an early stage of the disease.
Cancer that has spread beyond the prostate (such as to the bones,
lymph nodes, and lungs) is not curable, but it may be controlled for
many years. Because of the many advances in available treatments, most
men whose prostate cancer becomes widespread can expect to live five
years or more. Some men with advanced prostate cancer live a normal life
and die of another cause, such as heart disease.
What Causes Prostate Cancer?
Prostate cancer affects mainly older men. About 80% of cases are
in men over 65, and less than 1% of cases are in men under 50. Men with a
family history of prostate cancer are more likely to get it.
Doctors don’t know what causes prostate cancer, but diet
contributes to the risk. Men who eat lots of fat from red meat are most
likely to have prostate cancer. Eating meat may be risky for other
reasons: Meat cooked at high temperatures produces cancer-causing
substances that affect the prostate. The disease is much more common in
countries where meat and dairy products are common than in countries
where the diet consists of rice, soybean products, and vegetables.
Hormones also play a role. Eating fats raises the amount of
testosterone in the body, and testosterone speeds the growth of prostate
cancer.
A few job hazards have been found. Welders, battery
manufacturers, rubber workers, and workers frequently exposed to the
metal cadmium seem to be more likely to get prostate cancer.
Not exercising also makes prostate cancer more likely.
Drugs that may lower the risk of having prostate cancer include
aspirin, finasteride, cholesterol-lowering drugs and
triglyceride-lowering drugs, and anti-inflammatory drugs. Adding certain
foods in your diet may also help reduce the risk, including tomato
sauce and vegetables like broccoli, cauliflower, and cabbage.
Prostate Cancer Risk Factors
All men are at risk for developing prostate cancer. About one man in six will be diagnosed with prostate cancer
during his lifetime, but only one man in 36 will die of this disease.
About 80 percent of men who reach age 80 have prostate cancer cells in
their prostate. Besides being male, there are other factors, such as
age, race, and family history that may contribute to the risk.
Age. The greatest risk factor for prostate cancer is age.
This risk increases significantly after the age of 50 in white men who
have no family history of the disease and after the age of 40 in black
men and men who have a close relative with prostate cancer. About
two-thirds of all prostate cancers are diagnosed in men age 65 and
older.
Family history. Men whose relatives have had prostate
cancer are considered to be at high risk. Having a father or brother
with the disease more than doubles your risk for prostate cancer,
according to the American Cancer Society. Having a brother with prostate
cancer appears to increase your risk more than having an affected
father does. That risk is even higher when there are multiple family
members affected. Screening for prostate cancer should be started at age 40 in these men.
Studies have identified several inherited genes that appear to
increase prostate cancer risk. Testing for these genes is not yet
available. Experts estimate that the hereditary form of prostate cancer
accounts for just 5% to 10% of all cases.
Race. Prostate cancer occurs about 60% more often in
African American men than in white American men and when diagnosed is
more likely to be advanced. However, Japanese and African males living
in their native countries have a low incidence of prostate cancer. Rates
for these groups increase sharply when they immigrate to the U.S.
African Americans are the second group of men for whom prostate cancer testing should begin at age 40.
Some experts theorize that this suggests an environmental
connection, possibly related to high-fat diets, less exposure to the
sun, exposure to heavy metals such as cadmium, infectious agents, or smoking. To date, the reasons for these racial differences are not understood.
Diet. Research also suggests high dietary fat may be a
contributing factor for prostate cancer. The disease is much more common
in countries where meat and dairy products are dietary staples compared
to countries where the basic diet consists of rice, soybean products,
and vegetables.
Eating a diet high in the antioxidant lycopene (found in high levels in some fruits and vegetables,
such as tomatoes, pink grapefruit, and watermelon) may lower your risk
of developing prostate cancer according to several studies.
How Can I Prevent Prostate Cancer?
No evidence proves that you can prevent prostate cancer. But you may be able to lower your risk.
A diet that helps maintain a healthy weight may reduce your risk for prostate cancer. The American Cancer Society recommends:
- Limiting high-fat foods
- Cutting back on red meats, especially processed meats such as hot dogs, bologna, and certain lunch meats
- Eating five or more servings of fruits and vegetables each day
Healthy food choices also include bread, cereals, rice, pasta, and beans.
Antioxidants in foods, especially in fruits and vegetables, help
prevent damage to the DNA in the body's cells. Such damage has been
linked to cancer. Lycopene, in particular, is an antioxidant that has
been thought to lower the risk of prostate cancer. It can be found in
foods such as:
- Tomatoes -- both raw and cooked
- Spinach
- Artichoke hearts
- Beans
- Berries -- especially blueberries
- Pink grapefruit and oranges
- Watermelon
It's not clear whether lycopene actually helps prevent prostate
cancer, and recent studies have not been able to show that it does.
You may also start prostate complete for prevention: See below or follow this link to order:
https://sarfre.com/vitamins-health.php#!/Prostate-Complete-Dietary-Supplement/p/49263372
You may also start prostate complete for prevention: See below or follow this link to order:
https://sarfre.com/vitamins-health.php#!/Prostate-Complete-Dietary-Supplement/p/49263372
When to Seek Medical Care
See your health care provider if you have any of the following symptoms:
- Difficulty initiating and/or stopping a urine stream
- Frequent urination
- Pain on urination
- Pain on ejaculation
You should undergo regular screening for prostate cancer.
- Men aged 50 years and older should undergo a yearly digital
rectal examination and blood testing for prostatic specific antigen
(PSA).
- Men in the high-risk group, such as those with a family history of prostate cancer or of African American ethnicity, should begin screening as early as age 40 years.
Go to the nearest hospital emergency department right away if you have any of the following symptoms:
- Urinary tract infection - Burning pain on urination, urgency, frequent urination, especially with fever
- Bladder obstruction - Not urinating or urinating very little
despite drinking enough fluid; producing little urine despite straining;
pain due to a full bladder
- Acute kidney failure - Not urinating or urinating little, with little discomfort, despite drinking enough fluid
- Deep bone pain, especially in the back, hips, or thighs, or bone fracture - Possible sign of advanced prostate cancer that has spread to the bones
Spinal cord compression is a true emergency and may be the first
sign of cancer. It occurs when the cancer has spread to vertebrae of the
spine and tailbone region. The weakened vertebrae can collapse on the
spinal cord, causing symptoms and problems with function.
- Symptoms depend on the level at which the spine is compressed.
- Typical symptoms that might signal acute spinal cord
compression include weakness in the legs and difficulty walking,
increased difficulty urinating or moving your bowels, difficulty
controlling your bladder or bowels, and decreased sensation, numbness,
or tingling in the groin or legs.
- These are often preceded by pain in the hip (usually one sided) or back lasting a few days or weeks.
- Such symptoms require immediate evaluation in the nearest hospital emergency department. Failure to be treated immediately can result in permanent spinal cord damage.
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